Agnes Fogo, MD
Professor Vanderbilt University - Department of Pathology VUMC, MCN C-3310 1161 21st Ave. S., Nashville, TN 37232 USA Phone: (615) 322-3114 Fax: (615) 343-7023 Email: agnes.fogo@Vanderbilt.Edu
Research Interest:Hypertensive nephrosclerosis, PAI-1, renin angiotensin system, glomerulosclerosis, progression, regression. We are interested in mechanisms of sclerosis in FSGS, in particular early events determining sclerotic changes in varying morphologic types of FSGS, either primary or secondary types related to hypertension. We have focused on potential differences in sclerosis in Caucasian versus African-American populations. We are focused on the potential of remodeling of existing sclerosis, and interaction of macrophages and parenchymal cells in effecting sclerosis and interstitial fibrosis. We also are investigating the interactions of PAI-1, TGF-beta and angiotensin, using